Search results for "Middle East"

showing 10 items of 106 documents

Speleothems from the Middle East: An Example of Water Limited Environments in the SISAL Database

2019

The Middle East (ME) spans the transition between a temperate Mediterranean climate in the Levant to hyper-arid sub-tropical deserts in the southern part of the Arabian Peninsula (AP), with the complex alpine topography in the northeast feeding the Euphrates and Tigris rivers which support life in the Southeastern Fertile Crescent (FC). Climate projections predict severe drying in several parts of the ME in response to global warming, making it important to understand the controls of hydro-climate perturbations in the region. Here we discuss 23 ME speleothem stable oxygen isotope (δ18Occ) records from 16 sites from the SISAL_v1 database (Speleothem Isotope Synthesis and Analysis database), …

010506 paleontologygeology010504 meteorology & atmospheric sciencesPleistoceneδ18OCaveSpeleothemlcsh:GN281-289Palaeoclimatecomputer.software_genre01 natural sciencesMiddle Eastlcsh:StratigraphyIsotopesEarth and Planetary Sciences (miscellaneous)DeglaciationPrecipitationHolocenelcsh:QE640-6990105 earth and related environmental sciencesEarth-Surface Processesgeographygeography.geographical_feature_categoryDatabaseGlobal warmingLast Glacial MaximumSpeleothemlcsh:Human evolutionSISAL databasecomputerGeology
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Allium nazarenum (Amaryllidaceae), a new species of the section Codonoprasum from Israel

2017

Allium nazarenum, a new species of A. sect. Codonoprasum, is described and illustrated from Israel. Within this species, two well distinct subspecies have been recognized, represented by the subsp. nazarenum and subsp. ramonense respectively. The first one occurs in northern and central Israel, which falls within the Mediterranean bioclimate, while the second one is circumscribed to the Negev desert. Both taxa are diploid with 2n = 16 and are found on various substrata usually in the batha or steppic plant communities. This species shows close relationships with the species belonging to the A. staticiforme group, from which it differs in several relevant diacritic features. Its morphology, …

0106 biological sciencesMediterranean climatePlant ScienceSubspecies010603 evolutionary biology01 natural sciencesBotanyAllioideaeEcology Evolution Behavior and SystematicsTaxonomyMiddle eastbiologyLeaf anatomySettore BIO/02 - Botanica SistematicaAllioideae; Allium staticiforme; Karyology; Leaf anatomy; Middle east; TaxonomyPlant communitybiology.organism_classificationEcology Evolution Behavior and SystematicTaxonAllium staticiformeAlliumConservation statusAllioideaeTaxonomy (biology)Karyology010606 plant biology & botanyPhytotaxa
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Taxonomic investigations on Psoralea palaestina (Fabaceae), a critical species of Mediterranean flora

2016

Psoralea palaestina is a critical and unappreciated species described from Palestinian territories, and currently treated as synonym of P. bituminosa, nowadays known as Bituminaria bituminosa. Nomenclatural investigations allowed to ascertain that it was validly described for the first time by Bassi (1768) and not by Gouan (1773), as previously thought. Extensive taxonomic investigations revealed that this very peculiar legume is morphologically well differentiated from the other allied known species. Therefore, it has to be properly treated at specific level and transferred to the genus Bituminaria, thus proposing a new combination: Bituminaria palaestina. Based on literature, herbarium an…

0106 biological sciencesPsoraleeaeChorologyPlant Science010603 evolutionary biology01 natural sciencesBituminariaMiddle EastBituminaria; Endemic flora; Fodder grass; Middle East; Nomenclature; Psoraleeae; TaxonomyBituminaria endemic flora fodder grass Middle East nomenclature Psoraleeae taxonomy0502 economics and businessBotanyPsoraleeaeEudicotsEcology Evolution Behavior and SystematicsTaxonomybiologyNomenclatureSettore BIO/02 - Botanica SistematicaFodder grass05 social sciencesEndemic floraFabaceaebiology.organism_classificationBituminariaHerbariumBituminaria bituminosaTaxonomy (biology)050203 business & managementPhytotaxa
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Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

2018

How humans got their goatsLittle is known regarding the location and mode of the early domestication of animals such as goats for husbandry. To investigate the history of the goat, Dalyet al.sequenced mitochondrial and nuclear sequences from ancient specimens ranging from hundreds to thousands of years in age. Multiple wild populations contributed to the origin of modern goats during the Neolithic. Over time, one mitochondrial type spread and became dominant worldwide. However, at the whole-genome level, modern goat populations are a mix of goats from different sources and provide evidence for a multilocus process of domestication in the Near East. Furthermore, the patterns described suppor…

0301 basic medicineFollistatinMESH: DomesticationAGRICULTURE1103CATTLEMESH: FollistatinMESH: AfricaGenome[SHS]Humanities and Social SciencesDomestication0601 history and archaeologyMESH: AnimalsMESH: Genetic VariationMESH: PhylogenyPhylogenyZAGROSmedia_common2. Zero hunger[SDV.EE]Life Sciences [q-bio]/Ecology environmentGenome1311MultidisciplinaryMiddle East060102 archaeologyMosaicismMESH: AsiaGoats06 humanities and the artsEuropeAnimals DomesticMESH: MosaicismReproductionTRAITSAsia[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistorymedia_common.quotation_subject1204BiologyDNA MitochondrialMESH: GoatsMosaic03 medical and health sciencesPhylogeneticsGenetic variationAnimalsMESH: GenomeMESH: Animals DomesticDNA AncientDietary change[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Domestication[SDV.GEN]Life Sciences [q-bio]/GeneticsNEAR-EASTMESH: DNA MitochondrialGenetic VariationMESH: DNA AncientGENEMODEL030104 developmental biologySHEEPEvolutionary biologyORIGINSAfricaMESH: EuropeScience
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Fasciola hepatica eggs in paleofaeces of the Persian onager Equus hemionus onager, a donkey from Chehrabad archaeological site, dating back to the Sa…

2018

Fascioliasis is a highly pathogenic zoonotic disease caused by the liver trematodes Fasciola hepatica and F. gigantica. Within the multidisciplinary initiative against this disease, there is the aim of understanding how this disease reached a worldwide distribution, with important veterinary and medical repercussions, by elucidating the spreading steps followed by the two fasciolids from their paleobiogeograhical origins. Fasciola eggs were detected in paleofaeces of a donkey, probably the present-day endangered Persian onager Equus hemionus onager, found in the Chehrabad salt mine archaeological site, Zanjan province, northwestern Iran. The biological remains dated back to the Sassanid per…

0301 basic medicineMicrobiology (medical)Fascioliasis030231 tropical medicine610 Medicine & healthPersian onagerIranMicrobiology2726 Microbiology (medical)03 medical and health sciences0302 clinical medicine1311 GeneticsHepaticaparasitic diseasesGenetics1312 Molecular BiologyAnimalsDomesticationMolecular BiologyHistory AncientEcology Evolution Behavior and SystematicsMiddle EastFasciolabiologybusiness.industry2404 MicrobiologyEquidae2725 Infectious DiseasesFasciola hepatica030108 mycology & parasitologybiology.organism_classificationEquusArchaeologyHistory MedievalInfectious Diseases1105 Ecology Evolution Behavior and Systematics11294 Institute of Evolutionary MedicineLivestockDonkeybusiness
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Identification of novel compounds against three targets of SARS CoV-2 coronavirus by combined virtual screening and supervised machine learning.

2021

Coronavirus disease 2019 (COVID-19) is a major threat worldwide due to its fast spreading. As yet, there are no established drugs available. Speeding up drug discovery is urgently required. We applied a workflow of combined in silico methods (virtual drug screening, molecular docking and supervised machine learning algorithms) to identify novel drug candidates against COVID-19. We constructed chemical libraries consisting of FDA-approved drugs for drug repositioning and of natural compound datasets from literature mining and the ZINC database to select compounds interacting with SARS-CoV-2 target proteins (spike protein, nucleocapsid protein, and 2′-o-ribose methyltransferase). Supported by…

0301 basic medicineSimeprevirArtificial intelligencevirusesMERS Middle East Respiratory SyndromeHealth InformaticsBiologyMachine learningcomputer.software_genremedicine.disease_causeAntiviral AgentsArticleWHO World Health OrganizationAUC area under the curve03 medical and health sciences0302 clinical medicinessRNA single-stranded RNA virusmedicineChemotherapyHumansSARS severe acute respiratory syndromeCOVID-19 coronavirus disease 2019CoronavirusNatural productsVirtual screeningACE2 angiotensin converting enzyme 2Drug discoverybusiness.industrySARS-CoV-2COVID-19LBE lowest binding energyFDA Food and Drug AdministrationROC receiver operating characteristicComputer Science ApplicationsHIV human immunodeficiency virusMolecular Docking SimulationDrug repositioning030104 developmental biologyDrug developmentSevere acute respiratory syndrome-related coronavirusParitaprevirInfectious diseasesRespiratory virusArtificial intelligenceSupervised Machine Learningbusinesscomputer030217 neurology & neurosurgeryComputers in biology and medicine
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Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe

2019

International audience; Archaeological evidence indicates that pig domestication had begun by ∼10,500 y before the present (BP) in the Near East, and mitochondrial DNA (mtDNA) suggests that pigs arrived in Europe alongside farmers ∼8,500 y BP. A few thousand years after the introduction of Near Eastern pigs into Europe, however, their characteristic mtDNA signature disappeared and was replaced by haplotypes associated with European wild boars. This turnover could be accounted for by substantial gene flow from local Euro-pean wild boars, although it is also possible that European wild boars were domesticated independently without any genetic contribution from the Near East. To test these hyp…

0301 basic medicineSwine[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropologySkin Pigmentation[SHS]Humanities and Social SciencesGene flowDomesticationddc:590BREEDSDOMESTIC PIGS/dk/atira/pure/subjectarea/asjc/1000HISTORY0601 history and archaeologyNeolithicHistory AncientPhylogenyMultidisciplinary060102 archaeologyINTROGRESSIONEurope ; pigs ; domestication ; genomesWILD06 humanities and the artsArchaeological evidenceGene flowEuropeSPREADCoatMitochondrial DNAEvolutionZoology930Locus (genetics)BiologyAnimal Breeding and GenomicsDNA MitochondrialMiddle East03 medical and health sciencesAnimalsFokkerij en GenomicaDNA AncientGeneralDomesticationddc:930HaplotypeDNA900 Geschichte und Geografie::930 Geschichte des Altertums (bis ca. 499) Archäologie::930 Geschichte des Altertums bis ca. 499 ArchäologieLONGSIZE030104 developmental biologydomestication evolution gene flow NeolithicWIAS
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Statistical Explorations and Univariate Timeseries Analysis on COVID-19 Datasets to Understand the Trend of Disease Spreading and Death

2020

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0301 basic medicinetransmission ratepopulationSevere Acute Respiratory Syndromemedicine.disease_causelcsh:Chemical technologyBiochemistryRNNDisease OutbreaksAnalytical Chemistry0302 clinical medicinePandemiclcsh:TP1-1185030212 general & internal medicineInstrumentationVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550Coronaviruskeraseducation.field_of_studypublic healthartificial intelligenceAtomic and Molecular Physics and OpticsRegressionmachine learningGeographySevere acute respiratory syndrome-related coronavirusstatisticsMiddle East Respiratory Syndrome Coronaviruscommunity diseaseregressionCoronavirus InfectionsLSTMPneumonia ViralPopulationWorld Health OrganizationArticleBetacoronavirusspread factor03 medical and health sciencesCode (cryptography)medicineAnimalsHumansElectrical and Electronic EngineeringeducationPandemicsmeasurable sensor dataalgorithmSARS-CoV-2ICDUnivariatedeep learningOutbreakCOVID-19medicine.diseasehypothesis testpython030104 developmental biologycorrelationCatsMiddle East respiratory syndromeCattleDemographySensors
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Competition for long-haul connecting traffic among airports in Europe and the Middle East

2017

Abstract This paper analyzes the competitive position of major hub airports in Europe and the Middle East for long-haul connecting traffic. We apply a connection builder to construct competitive flight connections. A stand out feature of the proposed connection builder is the calibration of the model parameters using booking data, composed of actual passenger demand between a given origin and destination (O&D) market. The methodology is applied to measure competition between hubs using flight schedule data to calculate connectivity measures like the number of city-pairs connected via a hub airport. Our results show that the Middle Eastern hubs have improved their competitive position, while…

050210 logistics & transportationMiddle EastOperations researchbusiness.industry020209 energyStrategy and Management05 social sciencesTransportationModel parametersComputer Science::Social and Information Networks02 engineering and technologyManagement Monitoring Policy and LawCompetition (economics)Network management0502 economics and businessFlight schedule0202 electrical engineering electronic engineering information engineeringPosition (finance)businessTelecommunicationsLawJournal of Air Transport Management
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Organic residue analysis shows sub-regional patterns in the use of pottery by Northern European hunter–gatherers

2020

The introduction of pottery vessels to Europe has long been seen as closely linked with the spread of agriculture and pastoralism from the Near East. The adoption of pottery technology by hunter–gatherers in Northern and Eastern Europe does not fit this paradigm, and its role within these communities is so far unresolved. To investigate the motivations for hunter–gatherer pottery use, here, we present the systematic analysis of the contents of 528 early vessels from the Baltic Sea region, mostly dating to the late 6th–5th millennium cal BC, using molecular and isotopic characterization techniques. The results demonstrate clear sub-regional trends in the use of ceramics by hunter–gatherers; …

1001Earth and Environmental Sciencecircum-baltic area010506 paleontologyPastoralism69early neolithicorganic residue analysis01 natural scienceslate mesolithiccooking pottery0601 history and archaeologyhunter–gathererslcsh:Science0105 earth and related environmental sciencesMultidisciplinaryMiddle East060102 archaeologybusiness.industry7006 humanities and the artsArchaeologyGeographyAgriculturelcsh:QPotterybusinessResearch ArticleRoyal Society Open Science
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